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doi: 10.1016/j.metabol.2005.03.008

Product Specifications Form: Lyophilized Powder Blend Appearance: White to off-white powder Purity: 98% (per constituent) Storage: Store in a cool, dry environment

BAP1 regulates different mechanisms of cell death

Cholesterol-induced intestinal permeability allows the translocation of bacterial endotoxins, particularly LPS, into the portal circulation, triggering hepatic TLR4 activation, which promotes Kupffer cell activation, the release of inflammatory cytokines (TNF-, IL-6, IL-1), and insulin resistance [88, 89]